Science

Mango•xan® Antioxidant Formula is a wonderfully delicious and natural nutritional juice supplement made from the exotic curative Mangosteen fruit and other pure fruit juices. It has 2x plus more xanthones per serving than other brands (independent tests.) Contains antioxidants, which protect against free radicals.* Increases energy and stamina.* Supports the immune system.* Promotes a healthy digestive system.* Assists in recovery after exercise.* Supports joint and cartilage functionality (anti-inflammatory properties.)* GMO Free.

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The potential "fat burning" effects of the liquid dietary supplement Mangoxan

'Afa K. Palu1, Wayne Geilman2, and Brett J. West1. (1) Tahitian Noni International, American Fork, UT, (2) *Pure Fruit Technologies, American Fork, UT

Fruits have impacted our lives for centuries due to their potential health benefits including antioxidants, anticancer, immunomodulation, cell metabolism, and a host of other benefits. Such benefits have greatly increased the marketing and consumption of fruits in a variety of liquid dietary supplements. Among the health benefits attributed to fruit juices and other plant-based products is the achievement of a healthier weight, when used in conjunction with diet and exercise.

Such products often contain compound(s) that can bind to and stimulate ß-1 and ß-3 adrenergic receptors. These have been shown in scientific studies to increase energy, lipolysis and help maintain a healthier weight. To this end, we have investigated the in-vitro effects of a commercial liquid dietary supplement Mangoxan® (MX) on adrenergic receptors. With 2 replications each of 1 and 2.5% concentrations, the results showed a clear concentration-dependent binding to and stimulation of, ß-1 and ß-3 adrenergic receptors by MX. Interestingly, these binding and stimulation effects were more pronounced for ß-3 than for ß-1 adrenergic receptors: at 1%, ß-3 and ß-1 were 453 and 38%, respectively; at 2.5%, ß-3 and ß-1 were 463 and 58%, respectively. These results show that Mangoxan®, through this adrenergic stimulation mechanism, has the potential to increase energy and help maintain a healthier weight in conjunction with diet and exercise.

Further studies and clinical trial are therefore warranted to assess the dosage and efficacy of Mangoxan® concerning energy and weight managements in humans.